“ Metformin 500 mg 1 tablet 3 times a day NAC 600 mg 1 tablet 3 times a day All treatments were administered for 6 weeks Outcomes Oocyte and embryo quality Endocrine parameters Clinical pregnancy Side effects Notes Iran, study ran from July 2012 to February 2013 Need to clarify primary and secondary outcomes Author emailed regarding RoB, live birth and miscarriage information; no reply Funded by institutional grant Risk of bias Bias Authors judgement Support for judgement Random sequence generation selection bias Unclear risk State random but method not described Allocation concealment selection bias Unclear risk Not stated Blinding performance bias and detection bias All outcomes High risk Double blinded placebo controlled, but the placebo group received oral rehydration salts, which are usually in solution, while the treatments were tablets Incomplete outcome data attrition bias All outcomes High risk Dropouts accounted for, but 25 dropout Selective reporting reporting bias Low risk Outcomes reported Other bias Low risk No other bias found soft tab cialis As for rare side effects i under care of gynecologist and see him every 6 months ”