“ Almost all hormone responsive patients with metastatic tumors and 40 of those with non metastatic tumors who receive TAM as an adjuvant therapy eventually experience disease progression, with a deadly outcome 2 lasix and potassium The antigen specific immune response, cell mediated immune response or delayed type hypersensitivity immune response can be enhanced at least about 25, at least about 40, at least about 50, at least about 60, at least about 75 or at least about 90 ”